decreased cardiac muscle contractility_Pten<tm2Mak>/Pten<tm2Mak>,Tg(Ckmm-cre)5Khn/0,Tg(Myh6-Pik3ca)1Siz/0

http://metadb.riken.jp/0005140I129P2OlaHsdFVBPtentm2MakPtentm2MakTgCkmmcre5Khn0TgMyh6Pik3ca1Siz0TgCkmmcre5KhnTgMyh6Pik3ca1SizPtentm2Mak

decreased cardiac muscle contractility_Pten<tm2Mak>/Pten<tm2Mak>,Tg(Ckmm-cre)5Khn/0,Tg(Myh6-Pik3ca)1Siz/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 5, C Ronald Kahn
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182093
• transgene insertion 1, Seigo Izumo
  http://metadb.riken.jp/db/mgi_rdf/MGI:3619913
• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pten<tm2Mak>/Pten<tm2Mak>,Tg(Ckmm-cre)5Khn/0,Tg(Myh6-Pik3ca)1Siz/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Ckmm-cre)5Khn|Tg(Myh6-Pik3ca)1Siz|Pten<tm2Mak>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased cardiac muscle contractility
  http://purl.obolibrary.org/obo/MP_0005140

文献

http://purl.org/net/cito/citesAsAuthority

• Michael A. Crackower, et.al., Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways., Cell, 2002, 110
  http://rdf.ncbi.nlm.nih.gov/pubmed/12297047