decreased cardiac muscle contractility_Hif1a<tm3Rsjo>/Hif1a<tm3Rsjo>,Myl2<tm1(cre)Krc>/Myl2<+>

http://metadb.riken.jp/0005140I129S1Sv129S4SvJae129X1SvJC57BL6Hif1atm3RsjoHif1atm3RsjoMyl2tm1creKrcMyl2Myl2tm1creKrcHif1atm3RsjoMyl2

decreased cardiac muscle contractility_Hif1a<tm3Rsjo>/Hif1a<tm3Rsjo>,Myl2<tm1(cre)Krc>/Myl2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• myosin, light polypeptide 2, regulatory, cardiac, slow
  http://metadb.riken.jp/db/mgi_rdf/MGI:97272
• hypoxia inducible factor 1, alpha subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:106918

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hif1a<tm3Rsjo>/Hif1a<tm3Rsjo>,Myl2<tm1(cre)Krc>/Myl2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Myl2<tm1(cre)Krc>|Hif1a<tm3Rsjo>|Myl2<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased cardiac muscle contractility
  http://purl.obolibrary.org/obo/MP_0005140

文献

http://purl.org/net/cito/citesAsAuthority

• Yan. Huang, et.al., Cardiac myocyte-specific HIF-1alpha deletion alters vascularization, energy availability, calcium flux, and contractility in the normoxic heart., FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, 18
  http://rdf.ncbi.nlm.nih.gov/pubmed/15132980