decreased cardiac muscle contractility_Cacna1c<tm1Ggm>/Cacna1c<tm1Ggm>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0

http://metadb.riken.jp/0005140I129S1Sv129X1SvJFVBNCacna1ctm1GgmCacna1ctm1GgmA1cfTgMyh6creEsr11Jmk0A1cfTgMyh6creEsr11JmkCacna1ctm1Ggm

decreased cardiac muscle contractility_Cacna1c<tm1Ggm>/Cacna1c<tm1Ggm>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• APOBEC1 complementation factor
  http://metadb.riken.jp/db/mgi_rdf/MGI:1917115
• calcium channel, voltage-dependent, L type, alpha 1C subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:103013

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cacna1c<tm1Ggm>/Cacna1c<tm1Ggm>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• A1cf<Tg(Myh6-cre/Esr1*)1Jmk>|Cacna1c<tm1Ggm>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased cardiac muscle contractility
  http://purl.obolibrary.org/obo/MP_0005140

文献

http://purl.org/net/cito/citesAsAuthority

• Barbara. Rosati, et.al., Robust L-type calcium current expression following heterozygous knockout of the Cav1.2 gene in adult mouse heart., The Journal of physiology, 2011, 589
  http://rdf.ncbi.nlm.nih.gov/pubmed/21521762