decreased cardiac muscle contractility_Stat3<tm1Xyfu>/Stat3<tm1.1Xyfu>,Tg(Myh6-cre)2182Mds/0

http://metadb.riken.jp/0005140I129S1SvFVBNStat3tm1XyfuStat3tm11XyfuTgMyh6cre2182Mds0TgMyh6cre2182MdsStat3tm1XyfuStat3tm11Xyfu

decreased cardiac muscle contractility_Stat3<tm1Xyfu>/Stat3<tm1.1Xyfu>,Tg(Myh6-cre)2182Mds/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• signal transducer and activator of transcription 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:103038
• transgene insertion 2182, Michael D Schneider
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447636

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Stat3<tm1Xyfu>/Stat3<tm1.1Xyfu>,Tg(Myh6-cre)2182Mds/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Myh6-cre)2182Mds|Stat3<tm1Xyfu>|Stat3<tm1.1Xyfu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased cardiac muscle contractility
  http://purl.obolibrary.org/obo/MP_0005140

文献

http://purl.org/net/cito/citesAsAuthority

• Jörg J. Jacoby, et.al., Cardiomyocyte-restricted knockout of STAT3 results in higher sensitivity to inflammation, cardiac fibrosis, and heart failure with advanced age., Proceedings of the National Academy of Sciences of the United States of America, 2003, 100
  http://rdf.ncbi.nlm.nih.gov/pubmed/14566054