decreased cardiac muscle contractility_Ryr2<tm1Slh>/Ryr2<+>

http://metadb.riken.jp/0005140I129S7SvEvBrdC57BL6Ryr2tm1SlhRyr2Ryr2Ryr2tm1Slh

decreased cardiac muscle contractility_Ryr2<tm1Slh>/Ryr2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• ryanodine receptor 2, cardiac
  http://metadb.riken.jp/db/mgi_rdf/MGI:99685

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ryr2<tm1Slh>/Ryr2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ryr2<+>|Ryr2<tm1Slh>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased cardiac muscle contractility
  http://purl.obolibrary.org/obo/MP_0005140

文献

http://purl.org/net/cito/citesAsAuthority

• Prince J. Kannankeril, et.al., Mice with the R176Q cardiac ryanodine receptor mutation exhibit catecholamine-induced ventricular tachycardia and cardiomyopathy., Proceedings of the National Academy of Sciences of the United States of America, 2006, 103
  http://rdf.ncbi.nlm.nih.gov/pubmed/16873551