decreased cardiac muscle contractility_Raf1<tm2Bacc>/Raf1<tm2Bacc>,Tg(Myh6-cre)2182Mds/0

http://metadb.riken.jp/0005140IC57BL6JRaf1tm2BaccRaf1tm2BaccTgMyh6cre2182Mds0Raf1tm2BaccTgMyh6cre2182Mds

decreased cardiac muscle contractility_Raf1<tm2Bacc>/Raf1<tm2Bacc>,Tg(Myh6-cre)2182Mds/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• v-raf-leukemia viral oncogene 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97847
• transgene insertion 2182, Michael D Schneider
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447636

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Raf1<tm2Bacc>/Raf1<tm2Bacc>,Tg(Myh6-cre)2182Mds/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Raf1<tm2Bacc>|Tg(Myh6-cre)2182Mds

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased cardiac muscle contractility
  http://purl.obolibrary.org/obo/MP_0005140

文献

http://purl.org/net/cito/citesAsAuthority

• Osamu. Yamaguchi, et.al., Cardiac-specific disruption of the c-raf-1 gene induces cardiac dysfunction and apoptosis., The Journal of clinical investigation, 2004, 114
  http://rdf.ncbi.nlm.nih.gov/pubmed/15467832