increased circulating VLDL cholesterol level_Ldlr<tm1Her>/Ldlr<tm1Her>,Tg(APOC1)1Lmh/?

http://metadb.riken.jp/0005145I129S7SvEvBrdC57BL6Ldlrtm1HerLdlrtm1HerTgAPOC11LmhTgAPOC11LmhLdlrtm1Her

increased circulating VLDL cholesterol level_Ldlr<tm1Her>/Ldlr<tm1Her>,Tg(APOC1)1Lmh/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Louis M Havekes
  http://metadb.riken.jp/db/mgi_rdf/MGI:1926370
• low density lipoprotein receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:96765

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ldlr<tm1Her>/Ldlr<tm1Her>,Tg(APOC1)1Lmh/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(APOC1)1Lmh|Ldlr<tm1Her>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating VLDL cholesterol level
  http://purl.obolibrary.org/obo/MP_0005145

文献

http://purl.org/net/cito/citesAsAuthority

• M C. Jong, et.al., In the absence of the low density lipoprotein receptor, human apolipoprotein C1 overexpression in transgenic mice inhibits the hepatic uptake of very low density lipoproteins via a receptor-associated protein-sensitive pathway., The Journal of clinical investigation, 1996, 98
  http://rdf.ncbi.nlm.nih.gov/pubmed/8941642