increased B cell proliferation_Igh<tm2Mnz>/Igh<tm2Mnz>,Lyn<tm1Sor>/Lyn<tm1Sor>

http://metadb.riken.jp/0005154I129P2OlaHsd129S4SvJaeSorC57BL6Ightm2MnzIghtm2MnzLyntm1SorLyntm1SorLyntm1SorIghtm2Mnz

increased B cell proliferation_Igh<tm2Mnz>/Igh<tm2Mnz>,Lyn<tm1Sor>/Lyn<tm1Sor>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• LYN proto-oncogene, Src family tyrosine kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:96892
• immunoglobulin heavy chain complex
  http://metadb.riken.jp/db/mgi_rdf/MGI:96442

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Igh<tm2Mnz>/Igh<tm2Mnz>,Lyn<tm1Sor>/Lyn<tm1Sor>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lyn<tm1Sor>|Igh<tm2Mnz>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased B cell proliferation
  http://purl.obolibrary.org/obo/MP_0005154

文献

http://purl.org/net/cito/citesAsAuthority

• Tien-An Yang. Shih, et.al., Role of antigen receptor affinity in T cell-independent antibody responses in vivo., Nature immunology, 2002, 3
  http://rdf.ncbi.nlm.nih.gov/pubmed/11896394