holoprosencephaly_Acvr1b<tm1Enl>/Acvr1b<+>,Gdf1<tm1Sjl>/Gdf1<tm1Sjl>

http://metadb.riken.jp/0005157I129S1Sv129S4SvJae129X1SvJC57BL6Acvr1btm1EnlAcvr1bGdf1tm1SjlGdf1tm1SjlGdf1tm1SjlAcvr1bAcvr1btm1Enl

holoprosencephaly_Acvr1b<tm1Enl>/Acvr1b<+>,Gdf1<tm1Sjl>/Gdf1<tm1Sjl>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• activin A receptor, type 1B
  http://metadb.riken.jp/db/mgi_rdf/MGI:1338944
• growth differentiation factor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:95683

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Acvr1b<tm1Enl>/Acvr1b<+>,Gdf1<tm1Sjl>/Gdf1<tm1Sjl>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gdf1<tm1Sjl>|Acvr1b<+>|Acvr1b<tm1Enl>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• holoprosencephaly
  http://purl.obolibrary.org/obo/MP_0005157

文献

http://purl.org/net/cito/citesAsAuthority

• Olov. Andersson, et.al., Synergistic interaction between Gdf1 and Nodal during anterior axis development., Developmental biology, 2006, 293
  http://rdf.ncbi.nlm.nih.gov/pubmed/16564040