holoprosencephaly_Gas1<tm2Fan>/Gas1<tm2Fan>,Shh<tm1Chg>/Shh<+>

http://metadb.riken.jp/0005157I129Sv129S1Sv129X1SvJC57BL6JGas1tm2FanGas1tm2FanShhtm1ChgShhShhtm1ChgGas1tm2FanShh

holoprosencephaly_Gas1<tm2Fan>/Gas1<tm2Fan>,Shh<tm1Chg>/Shh<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• growth arrest specific 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:95655
• sonic hedgehog
  http://metadb.riken.jp/db/mgi_rdf/MGI:98297

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gas1<tm2Fan>/Gas1<tm2Fan>,Shh<tm1Chg>/Shh<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Shh<tm1Chg>|Gas1<tm2Fan>|Shh<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * 129S1/Sv * 129X1/SvJ * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• holoprosencephaly
  http://purl.obolibrary.org/obo/MP_0005157

文献

http://purl.org/net/cito/citesAsAuthority

• David C. Martinelli, et.al., Gas1 extends the range of Hedgehog action by facilitating its signaling., Genes & development, 2007, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/17504940