abnormal blood-brain barrier function_Aqp4<tm1.1Geno>/Aqp4<tm1.1Geno>,Tg(GFAP-cre)25Mes/0

http://metadb.riken.jp/0005167IC57BL6JFVBNAqp4tm11GenoAqp4tm11GenoTgGFAPcre25Mes0TgGFAPcre25MesAqp4tm11Geno

abnormal blood-brain barrier function_Aqp4<tm1.1Geno>/Aqp4<tm1.1Geno>,Tg(GFAP-cre)25Mes/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 25, Albee Messing
  http://metadb.riken.jp/db/mgi_rdf/MGI:2179047
• aquaporin 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:107387

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Aqp4<tm1.1Geno>/Aqp4<tm1.1Geno>,Tg(GFAP-cre)25Mes/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(GFAP-cre)25Mes|Aqp4<tm1.1Geno>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6J * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal blood-brain barrier function
  http://purl.obolibrary.org/obo/MP_0005167

文献

http://purl.org/net/cito/citesAsAuthority

• Nadia Nabil. Haj-Yasein, et.al., Glial-conditional deletion of aquaporin-4 (Aqp4) reduces blood-brain water uptake and confers barrier function on perivascular astrocyte endfeet., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/21990350