abnormal male meiosis_Brca1<tm2.1Cxd>/Brca1<tm2.1Cxd>,Trp53<tm1Brd>/Trp53<+>

http://metadb.riken.jp/0005169I129S6SvEvTac129S7SvEvBrdBlackSwissFVBBrca1tm21CxdBrca1tm21CxdTrp53tm1BrdTrp53Trp53tm1BrdBrca1tm21CxdTrp53

abnormal male meiosis_Brca1<tm2.1Cxd>/Brca1<tm2.1Cxd>,Trp53<tm1Brd>/Trp53<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• breast cancer 1, early onset
  http://metadb.riken.jp/db/mgi_rdf/MGI:104537
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Brca1<tm2.1Cxd>/Brca1<tm2.1Cxd>,Trp53<tm1Brd>/Trp53<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Brd>|Brca1<tm2.1Cxd>|Trp53<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * 129S7/SvEvBrd * Black Swiss * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal male meiosis
  http://purl.obolibrary.org/obo/MP_0005169

文献

http://purl.org/net/cito/citesAsAuthority

• Xiaoling. Xu, et.al., Impaired meiotic DNA-damage repair and lack of crossing-over during spermatogenesis in BRCA1 full-length isoform deficient mice., Development (Cambridge, England), 2003, 130
  http://rdf.ncbi.nlm.nih.gov/pubmed/12642502