increased circulating cholesterol level_Apobec1<tm1Ddsn>/Apobec1<tm1Ddsn>,Ldlr<tm1Her>/Ldlr<tm1Her>

http://metadb.riken.jp/0005178I129S4SvJae129S7SvEvBrdC57BL6Apobec1tm1DdsnApobec1tm1DdsnLdlrtm1HerLdlrtm1HerLdlrtm1HerApobec1tm1Ddsn

increased circulating cholesterol level_Apobec1<tm1Ddsn>/Apobec1<tm1Ddsn>,Ldlr<tm1Her>/Ldlr<tm1Her>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:103298
• low density lipoprotein receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:96765

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apobec1<tm1Ddsn>/Apobec1<tm1Ddsn>,Ldlr<tm1Her>/Ldlr<tm1Her>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ldlr<tm1Her>|Apobec1<tm1Ddsn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating cholesterol level
  http://purl.obolibrary.org/obo/MP_0005178

文献

http://purl.org/net/cito/citesAsAuthority

• L. Powell-Braxton, et.al., A mouse model of human familial hypercholesterolemia: markedly elevated low density lipoprotein cholesterol levels and severe atherosclerosis on a low-fat chow diet., Nature medicine, 1998, 4
  http://rdf.ncbi.nlm.nih.gov/pubmed/9701246