decreased circulating cholesterol level_Por<tm1Ding>/Por<tm1Ding>,Tg(Alb-cre)21Mgn/0

http://metadb.riken.jp/0005179I129S1SvC57BL6DBAPortm1DingPortm1DingTgAlbcre21Mgn0Portm1DingTgAlbcre21Mgn

decreased circulating cholesterol level_Por<tm1Ding>/Por<tm1Ding>,Tg(Alb-cre)21Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226
• P450 (cytochrome) oxidoreductase
  http://metadb.riken.jp/db/mgi_rdf/MGI:97744

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Por<tm1Ding>/Por<tm1Ding>,Tg(Alb-cre)21Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Por<tm1Ding>|Tg(Alb-cre)21Mgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased circulating cholesterol level
  http://purl.obolibrary.org/obo/MP_0005179

文献

http://purl.org/net/cito/citesAsAuthority

• Jun. Gu, et.al., Liver-specific deletion of the NADPH-cytochrome P450 reductase gene: impact on plasma cholesterol homeostasis and the function and regulation of microsomal cytochrome P450 and heme oxygenase., The Journal of biological chemistry, 2003, 278
  http://rdf.ncbi.nlm.nih.gov/pubmed/12697746