decreased circulating cholesterol level_Angptl3<tm1Lex>/Angptl3<tm1Lex>,Ldlr<tm1Her>/Ldlr<tm1Her>

http://metadb.riken.jp/0005179I129S5SvEvBrd129S7SvEvBrdC57BL6Angptl3tm1LexAngptl3tm1LexLdlrtm1HerLdlrtm1HerAngptl3tm1LexLdlrtm1Her

decreased circulating cholesterol level_Angptl3<tm1Lex>/Angptl3<tm1Lex>,Ldlr<tm1Her>/Ldlr<tm1Her>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• low density lipoprotein receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:96765
• angiopoietin-like 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1353627

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Angptl3<tm1Lex>/Angptl3<tm1Lex>,Ldlr<tm1Her>/Ldlr<tm1Her>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Angptl3<tm1Lex>|Ldlr<tm1Her>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S5/SvEvBrd * 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased circulating cholesterol level
  http://purl.obolibrary.org/obo/MP_0005179

文献

http://purl.org/net/cito/citesAsAuthority

• E-Chiang. Lee, et.al., Identification of a new functional domain in angiopoietin-like 3 (ANGPTL3) and angiopoietin-like 4 (ANGPTL4) involved in binding and inhibition of lipoprotein lipase (LPL)., The Journal of biological chemistry, 2009, 284
  http://rdf.ncbi.nlm.nih.gov/pubmed/19318355