increased circulating estradiol level_Foxo1<tm1Rdp>/Foxo1<tm1.1Rdp>,Foxo3<tm1Rdp>/Foxo3<tm1.1Rdp>,Amhr2<tm3(cre)Bhr>/Amhr2<+>

http://metadb.riken.jp/0005182I129S6SvEvTac129S7SvEvBrdFoxo1tm1RdpFoxo1tm11RdpFoxo3tm1RdpFoxo3tm11RdpAmhr2tm3creBhrAmhr2Foxo1tm11RdpFoxo3tm11RdpAmhr2tm3creBhrFoxo3tm1RdpFoxo1tm1RdpAmhr2

increased circulating estradiol level_Foxo1<tm1Rdp>/Foxo1<tm1.1Rdp>,Foxo3<tm1Rdp>/Foxo3<tm1.1Rdp>,Amhr2<tm3(cre)Bhr>/Amhr2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• forkhead box O3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1890081
• anti-Mullerian hormone type 2 receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:105062
• forkhead box O1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1890077

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Foxo1<tm1Rdp>/Foxo1<tm1.1Rdp>,Foxo3<tm1Rdp>/Foxo3<tm1.1Rdp>,Amhr2<tm3(cre)Bhr>/Amhr2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Foxo1<tm1.1Rdp>|Foxo3<tm1.1Rdp>|Amhr2<tm3(cre)Bhr>|Foxo3<tm1Rdp>|Foxo1<tm1Rdp>|Amhr2<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * 129S7/SvEvBrd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating estradiol level
  http://purl.obolibrary.org/obo/MP_0005182

文献

http://purl.org/net/cito/citesAsAuthority

• Zhilin. Liu, et.al., FOXO1/3 and PTEN Depletion in Granulosa Cells Promotes Ovarian Granulosa Cell Tumor Development., Molecular endocrinology (Baltimore, Md.), 2015, 29
  http://rdf.ncbi.nlm.nih.gov/pubmed/26061565