abnormal pancreatic islet morphology_Neurog3<tm1.1(cre/ERT)Ggu>/Neurog3<+>,Pdx1<tm1Macd>/Pdx1<+>,Tg(tetO-Myt1)2Ggu/0

http://metadb.riken.jp/0005215I129S1Sv129S6SvEvTac129X1SvJNeurog3tm11creERTGguNeurog3Pdx1tm1MacdPdx1TgtetOMyt12Ggu0Neurog3tm11creERTGguPdx1Pdx1tm1MacdTgtetOMyt12GguNeurog3

abnormal pancreatic islet morphology_Neurog3<tm1.1(cre/ERT)Ggu>/Neurog3<+>,Pdx1<tm1Macd>/Pdx1<+>,Tg(tetO-Myt1)2Ggu/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 2, Guoqiang Gu
  http://metadb.riken.jp/db/mgi_rdf/MGI:3809508
• pancreatic and duodenal homeobox 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:102851
• neurogenin 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:893591

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Neurog3<tm1.1(cre/ERT)Ggu>/Neurog3<+>,Pdx1<tm1Macd>/Pdx1<+>,Tg(tetO-Myt1)2Ggu/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Neurog3<tm1.1(cre/ERT)Ggu>|Pdx1<+>|Pdx1<tm1Macd>|Tg(tetO-Myt1)2Ggu|Neurog3<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal pancreatic islet morphology
  http://purl.obolibrary.org/obo/MP_0005215

文献

http://purl.org/net/cito/citesAsAuthority

• Sui. Wang, et.al., Myt1 and Ngn3 form a feed-forward expression loop to promote endocrine islet cell differentiation., Developmental biology, 2008, 317
  http://rdf.ncbi.nlm.nih.gov/pubmed/18394599