abnormal pancreatic alpha cell morphology_Ins1<tm1Jja>/Ins1<tm1Jja>,Ins2<tm1Jja>/Ins2<+>

http://metadb.riken.jp/0005216I129S2SvPasC57BL6Ins1tm1JjaIns1tm1JjaIns2tm1JjaIns2Ins2tm1JjaIns2Ins1tm1Jja

abnormal pancreatic alpha cell morphology_Ins1<tm1Jja>/Ins1<tm1Jja>,Ins2<tm1Jja>/Ins2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• insulin II
  http://metadb.riken.jp/db/mgi_rdf/MGI:96573
• insulin I
  http://metadb.riken.jp/db/mgi_rdf/MGI:96572

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ins1<tm1Jja>/Ins1<tm1Jja>,Ins2<tm1Jja>/Ins2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ins2<tm1Jja>|Ins2<+>|Ins1<tm1Jja>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal pancreatic alpha cell morphology
  http://purl.obolibrary.org/obo/MP_0005216

文献

http://purl.org/net/cito/citesAsAuthority

• B. Duvillié, et.al., Increased islet cell proliferation, decreased apoptosis, and greater vascularization leading to beta-cell hyperplasia in mutant mice lacking insulin., Endocrinology, 2002, 143
  http://rdf.ncbi.nlm.nih.gov/pubmed/11897712