abnormal pancreatic beta cell morphology_Insr<tm1Dac>/Insr<+>,Irs2<tm1Mfw>/Irs2<tm1Mfw>

http://metadb.riken.jp/0005217I129S1Sv129S4SvJae129X1SvJC57BL6Insrtm1DacInsrIrs2tm1MfwIrs2tm1MfwIrs2tm1MfwInsrInsrtm1Dac

abnormal pancreatic beta cell morphology_Insr<tm1Dac>/Insr<+>,Irs2<tm1Mfw>/Irs2<tm1Mfw>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• insulin receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:96575
• insulin receptor substrate 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:109334

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Insr<tm1Dac>/Insr<+>,Irs2<tm1Mfw>/Irs2<tm1Mfw>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Irs2<tm1Mfw>|Insr<+>|Insr<tm1Dac>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal pancreatic beta cell morphology
  http://purl.obolibrary.org/obo/MP_0005217

文献

http://purl.org/net/cito/citesAsAuthority

• Tadahiro. Kitamura, et.al., The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth., The Journal of clinical investigation, 2002, 110
  http://rdf.ncbi.nlm.nih.gov/pubmed/12488434