abnormal pancreatic beta cell morphology_Irs2<tm1Mfw>/Irs2<tm1Mfw>,Tg(Ins2-Irs2)13Mfw/0

http://metadb.riken.jp/0005217I129S1Sv129X1SvJC57BL6Irs2tm1MfwIrs2tm1MfwTgIns2Irs213Mfw0TgIns2Irs213MfwIrs2tm1Mfw

abnormal pancreatic beta cell morphology_Irs2<tm1Mfw>/Irs2<tm1Mfw>,Tg(Ins2-Irs2)13Mfw/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• insulin receptor substrate 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:109334
• transgene insertion 13, Morris F White
  http://metadb.riken.jp/db/mgi_rdf/MGI:3510674

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Irs2<tm1Mfw>/Irs2<tm1Mfw>,Tg(Ins2-Irs2)13Mfw/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Ins2-Irs2)13Mfw|Irs2<tm1Mfw>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal pancreatic beta cell morphology
  http://purl.obolibrary.org/obo/MP_0005217

文献

http://purl.org/net/cito/citesAsAuthority

• Anita M. Hennige, et.al., Upregulation of insulin receptor substrate-2 in pancreatic beta cells prevents diabetes., The Journal of clinical investigation, 2003, 112
  http://rdf.ncbi.nlm.nih.gov/pubmed/14617753