abnormal cholesterol homeostasis_Scap<tm1Mbjg>/Scap<tm1Mbjg>,Tg(Mx1-cre)29-4Her/0

http://metadb.riken.jp/0005278I129S6SvEvTacC57BL6JSJLScaptm1MbjgScaptm1MbjgTgMx1cre294Her0TgMx1cre294HerScaptm1Mbjg

abnormal cholesterol homeostasis_Scap<tm1Mbjg>/Scap<tm1Mbjg>,Tg(Mx1-cre)29-4Her/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 29-4, Joachim Herz
  http://metadb.riken.jp/db/mgi_rdf/MGI:2180898
• SREBF chaperone
  http://metadb.riken.jp/db/mgi_rdf/MGI:2135958

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Scap<tm1Mbjg>/Scap<tm1Mbjg>,Tg(Mx1-cre)29-4Her/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Mx1-cre)29-4Her|Scap<tm1Mbjg>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6J * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal cholesterol homeostasis
  http://purl.obolibrary.org/obo/MP_0005278

文献

http://purl.org/net/cito/citesAsAuthority

• M. Matsuda, et.al., SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevation., Genes & development, 2001, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/11358865