abnormal cholesterol homeostasis_Ldlr<tm1Her>/Ldlr<tm1Her>,Nr1h3<tm1.1Djm>/Nr1h3<tm1.1Djm>,Tg(Alb-cre)21Mgn/0

http://metadb.riken.jp/0005278I129SSvEv129S7SvEvBrdC57BL6DBALdlrtm1HerLdlrtm1HerNr1h3tm11DjmNr1h3tm11DjmTgAlbcre21Mgn0Nr1h3tm11DjmTgAlbcre21MgnLdlrtm1Her

abnormal cholesterol homeostasis_Ldlr<tm1Her>/Ldlr<tm1Her>,Nr1h3<tm1.1Djm>/Nr1h3<tm1.1Djm>,Tg(Alb-cre)21Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• nuclear receptor subfamily 1, group H, member 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1352462
• low density lipoprotein receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:96765
• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ldlr<tm1Her>/Ldlr<tm1Her>,Nr1h3<tm1.1Djm>/Nr1h3<tm1.1Djm>,Tg(Alb-cre)21Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Nr1h3<tm1.1Djm>|Tg(Alb-cre)21Mgn|Ldlr<tm1Her>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * 129S7/SvEvBrd * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal cholesterol homeostasis
  http://purl.obolibrary.org/obo/MP_0005278

文献

http://purl.org/net/cito/citesAsAuthority

• Yuan. Zhang, et.al., Liver LXRα expression is crucial for whole body cholesterol homeostasis and reverse cholesterol transport in mice., The Journal of clinical investigation, 2012, 122
  http://rdf.ncbi.nlm.nih.gov/pubmed/22484817