impaired glucose tolerance_Pdx1<tm1Ted>/Pdx1<+>

http://metadb.riken.jp/0005293I129P2OlaHsdPdx1tm1TedPdx1Pdx1tm1TedPdx1

impaired glucose tolerance_Pdx1<tm1Ted>/Pdx1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• pancreatic and duodenal homeobox 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:102851

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pdx1<tm1Ted>/Pdx1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pdx1<tm1Ted>|Pdx1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired glucose tolerance
  http://purl.obolibrary.org/obo/MP_0005293

文献

http://purl.org/net/cito/citesAsAuthority

• James D. Johnson, et.al., Increased islet apoptosis in Pdx1+/- mice., The Journal of clinical investigation, 2003, 111
  http://rdf.ncbi.nlm.nih.gov/pubmed/12697734
• U. Ahlgren, et.al., beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes., Genes & development, 1998, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/9637677