impaired glucose tolerance_Irs2<tm1Mfw>/Irs2<tm1Mfw>,Ptpn1<tm1Bbk>/Ptpn1<tm1Bbk>

http://metadb.riken.jp/0005293I129S1Sv129X1SvJC57BL6Irs2tm1MfwIrs2tm1MfwPtpn1tm1BbkPtpn1tm1BbkIrs2tm1MfwPtpn1tm1Bbk

impaired glucose tolerance_Irs2<tm1Mfw>/Irs2<tm1Mfw>,Ptpn1<tm1Bbk>/Ptpn1<tm1Bbk>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• insulin receptor substrate 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:109334
• protein tyrosine phosphatase, non-receptor type 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97805

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Irs2<tm1Mfw>/Irs2<tm1Mfw>,Ptpn1<tm1Bbk>/Ptpn1<tm1Bbk>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Irs2<tm1Mfw>|Ptpn1<tm1Bbk>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired glucose tolerance
  http://purl.obolibrary.org/obo/MP_0005293

文献

http://purl.org/net/cito/citesAsAuthority

• Jake A. Kushner, et.al., Islet-sparing effects of protein tyrosine phosphatase-1b deficiency delays onset of diabetes in IRS2 knockout mice., Diabetes, 2004, 53
  http://rdf.ncbi.nlm.nih.gov/pubmed/14693698