impaired glucose tolerance_Chrm3<tm2Jwe>/Chrm3<tm2Jwe>,Tg(Ins2-cre)25Mgn/0

http://metadb.riken.jp/0005293I129S6SvEvTacC57BL6DBAChrm3tm2JweChrm3tm2JweTgIns2cre25Mgn0Chrm3tm2JweTgIns2cre25Mgn

impaired glucose tolerance_Chrm3<tm2Jwe>/Chrm3<tm2Jwe>,Tg(Ins2-cre)25Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 25, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176225
• cholinergic receptor, muscarinic 3, cardiac
  http://metadb.riken.jp/db/mgi_rdf/MGI:88398

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Chrm3<tm2Jwe>/Chrm3<tm2Jwe>,Tg(Ins2-cre)25Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Chrm3<tm2Jwe>|Tg(Ins2-cre)25Mgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired glucose tolerance
  http://purl.obolibrary.org/obo/MP_0005293

文献

http://purl.org/net/cito/citesAsAuthority

• Dinesh. Gautam, et.al., A critical role for beta cell M3 muscarinic acetylcholine receptors in regulating insulin release and blood glucose homeostasis in vivo., Cell metabolism, 2006, 3
  http://rdf.ncbi.nlm.nih.gov/pubmed/16753580