impaired glucose tolerance_Hnf4a<tm1.1Gonz>/Hnf4a<tm1.1Gonz>,Tg(Ins2-cre)25Mgn/0

http://metadb.riken.jp/0005293I129X1SvJC57BL6DBAHnf4atm11GonzHnf4atm11GonzTgIns2cre25Mgn0Hnf4atm11GonzTgIns2cre25Mgn

impaired glucose tolerance_Hnf4a<tm1.1Gonz>/Hnf4a<tm1.1Gonz>,Tg(Ins2-cre)25Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• hepatic nuclear factor 4, alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:109128
• transgene insertion 25, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176225

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hnf4a<tm1.1Gonz>/Hnf4a<tm1.1Gonz>,Tg(Ins2-cre)25Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Hnf4a<tm1.1Gonz>|Tg(Ins2-cre)25Mgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129X1/SvJ * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired glucose tolerance
  http://purl.obolibrary.org/obo/MP_0005293

文献

http://purl.org/net/cito/citesAsAuthority

• Atsuko. Miura, et.al., Hepatocyte nuclear factor-4alpha is essential for glucose-stimulated insulin secretion by pancreatic beta-cells., The Journal of biological chemistry, 2006, 281
  http://rdf.ncbi.nlm.nih.gov/pubmed/16377800