abnormal corneal stroma morphology_Klf4<tm1Khk>/Klf4<tm1Khk>,Tg(Pax6-cre,GFP)1Pgr/0

http://metadb.riken.jp/0005300I129S6SvEvTacFVBNKlf4tm1KhkKlf4tm1KhkTgPax6creGFP1Pgr0Klf4tm1KhkTgPax6creGFP1Pgr

abnormal corneal stroma morphology_Klf4<tm1Khk>/Klf4<tm1Khk>,Tg(Pax6-cre,GFP)1Pgr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Kruppel-like factor 4 (gut)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1342287
• transgene insertion 1, Peter Gruss
  http://metadb.riken.jp/db/mgi_rdf/MGI:3045750

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Klf4<tm1Khk>/Klf4<tm1Khk>,Tg(Pax6-cre,GFP)1Pgr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Klf4<tm1Khk>|Tg(Pax6-cre,GFP)1Pgr

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal corneal stroma morphology
  http://purl.obolibrary.org/obo/MP_0005300

文献

http://purl.org/net/cito/citesAsAuthority

• Shivalingappa K. Swamynathan, et.al., Conditional deletion of the mouse Klf4 gene results in corneal epithelial fragility, stromal edema, and loss of conjunctival goblet cells., Molecular and cellular biology, 2007, 27
  http://rdf.ncbi.nlm.nih.gov/pubmed/17060454