insulin resistance_Irs1<tm2Tka>/Irs1<tm2Tka>,Irs2<tm2Tka>/Irs2<tm2Tka>,Tg(Alb-cre)21Mgn/0

http://metadb.riken.jp/0005331I129P2OlaHsd129S4SvJaeC57BL6DBAIrs1tm2TkaIrs1tm2TkaIrs2tm2TkaIrs2tm2TkaTgAlbcre21Mgn0TgAlbcre21MgnIrs2tm2TkaIrs1tm2Tka

insulin resistance_Irs1<tm2Tka>/Irs1<tm2Tka>,Irs2<tm2Tka>/Irs2<tm2Tka>,Tg(Alb-cre)21Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• insulin receptor substrate 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:109334
• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226
• insulin receptor substrate 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:99454

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Irs1<tm2Tka>/Irs1<tm2Tka>,Irs2<tm2Tka>/Irs2<tm2Tka>,Tg(Alb-cre)21Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Alb-cre)21Mgn|Irs2<tm2Tka>|Irs1<tm2Tka>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• insulin resistance
  http://purl.obolibrary.org/obo/MP_0005331

文献

http://purl.org/net/cito/citesAsAuthority

• Naoto. Kubota, et.al., Dynamic functional relay between insulin receptor substrate 1 and 2 in hepatic insulin signaling during fasting and feeding., Cell metabolism, 2008, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/18590692