insulin resistance_Irs2<tm2Tka>/Irs2<tm2Tka>,Tg(Alb-cre)21Mgn/0

http://metadb.riken.jp/0005331I129S4SvJaeC57BL6DBAIrs2tm2TkaIrs2tm2TkaTgAlbcre21Mgn0Irs2tm2TkaTgAlbcre21Mgn

insulin resistance_Irs2<tm2Tka>/Irs2<tm2Tka>,Tg(Alb-cre)21Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226
• insulin receptor substrate 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:109334

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Irs2<tm2Tka>/Irs2<tm2Tka>,Tg(Alb-cre)21Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Irs2<tm2Tka>|Tg(Alb-cre)21Mgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * DBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• insulin resistance
  http://purl.obolibrary.org/obo/MP_0005331

文献

http://purl.org/net/cito/citesAsAuthority

• Naoto. Kubota, et.al., Dynamic functional relay between insulin receptor substrate 1 and 2 in hepatic insulin signaling during fasting and feeding., Cell metabolism, 2008, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/18590692