insulin resistance_Irs2<tm1Tka>/Irs2<tm1Tka>

http://metadb.riken.jp/0005331IC57BL6CBAIrs2tm1TkaIrs2tm1TkaIrs2tm1Tka

insulin resistance_Irs2<tm1Tka>/Irs2<tm1Tka>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• insulin receptor substrate 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:109334

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Irs2<tm1Tka>/Irs2<tm1Tka>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Irs2<tm1Tka>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• insulin resistance
  http://purl.obolibrary.org/obo/MP_0005331

文献

http://purl.org/net/cito/citesAsAuthority

• N. Kubota, et.al., Disruption of insulin receptor substrate 2 causes type 2 diabetes because of liver insulin resistance and lack of compensatory beta-cell hyperplasia., Diabetes, 2000, 49
  http://rdf.ncbi.nlm.nih.gov/pubmed/11078455
• Tetsuya. Kubota, et.al., Lack of insulin receptor substrate-2 causes progressive neointima formation in response to vessel injury., Circulation, 2003, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/12810606