insulin resistance_Blvra<tm1c(EUCOMM)Hmgu>/Blvra<tm1c(EUCOMM)Hmgu>,Tg(Alb-cre)21Mgn/0

http://metadb.riken.jp/0005331IC57BL6JC57BL6NBlvratm1cEUCOMMHmguBlvratm1cEUCOMMHmguTgAlbcre21Mgn0Blvratm1cEUCOMMHmguTgAlbcre21Mgn

insulin resistance_Blvra<tm1c(EUCOMM)Hmgu>/Blvra<tm1c(EUCOMM)Hmgu>,Tg(Alb-cre)21Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226
• biliverdin reductase A
  http://metadb.riken.jp/db/mgi_rdf/MGI:88170

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Blvra<tm1c(EUCOMM)Hmgu>/Blvra<tm1c(EUCOMM)Hmgu>,Tg(Alb-cre)21Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Blvra<tm1c(EUCOMM)Hmgu>|Tg(Alb-cre)21Mgn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6J * C57BL/6N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• insulin resistance
  http://purl.obolibrary.org/obo/MP_0005331

文献

http://purl.org/net/cito/citesAsAuthority

• Terry D. Hinds, et.al., Biliverdin Reductase A Attenuates Hepatic Steatosis by Inhibition of Glycogen Synthase Kinase (GSK) 3β Phosphorylation of Serine 73 of Peroxisome Proliferator-activated Receptor (PPAR) α., The Journal of biological chemistry, 2016, 291
  http://rdf.ncbi.nlm.nih.gov/pubmed/27738106