insulin resistance_Tg(Ckm-PTPN1)45Bbk/?,Tg(Ckm-PTPRF)13Bbk/?

http://metadb.riken.jp/0005331IFVBTgCkmPTPN145BbkTgCkmPTPRF13BbkTgCkmPTPRF13BbkTgCkmPTPN145Bbk

insulin resistance_Tg(Ckm-PTPN1)45Bbk/?,Tg(Ckm-PTPRF)13Bbk/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 13, Barbara B Kahn
  http://metadb.riken.jp/db/mgi_rdf/MGI:3717652
• transgene insertion 45, Barbara B Kahn
  http://metadb.riken.jp/db/mgi_rdf/MGI:3717653

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Ckm-PTPN1)45Bbk/?,Tg(Ckm-PTPRF)13Bbk/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Ckm-PTPRF)13Bbk|Tg(Ckm-PTPN1)45Bbk

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• insulin resistance
  http://purl.obolibrary.org/obo/MP_0005331

文献

http://purl.org/net/cito/citesAsAuthority

• Janice M. Zabolotny, et.al., Transgenic overexpression of protein-tyrosine phosphatase 1B in muscle causes insulin resistance, but overexpression with leukocyte antigen-related phosphatase does not additively impair insulin action., The Journal of biological chemistry, 2004, 279
  http://rdf.ncbi.nlm.nih.gov/pubmed/15031294