increased susceptibility to atherosclerosis_Apoe<tm1Lmh>/Apoe<tm1Lmh>,Ldlr<tm1Her>/Ldlr<tm1Her>,Lrp1<tm2Her>/Lrp1<tm2Her>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

http://metadb.riken.jp/0005339I129P2OlaHsd129S7SvEvBrdApoetm1LmhApoetm1LmhLdlrtm1HerLdlrtm1HerLrp1tm2HerLrp1tm2HerLyz2tm1creIfoLyz2Ldlrtm1HerApoetm1LmhLyz2Lrp1tm2HerLyz2tm1creIfo

increased susceptibility to atherosclerosis_Apoe<tm1Lmh>/Apoe<tm1Lmh>,Ldlr<tm1Her>/Ldlr<tm1Her>,Lrp1<tm2Her>/Lrp1<tm2Her>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• apolipoprotein E
  http://metadb.riken.jp/db/mgi_rdf/MGI:88057
• low density lipoprotein receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:96765
• low density lipoprotein receptor-related protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:96828
• lysozyme 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:96897

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apoe<tm1Lmh>/Apoe<tm1Lmh>,Ldlr<tm1Her>/Ldlr<tm1Her>,Lrp1<tm2Her>/Lrp1<tm2Her>,Lyz2<tm1(cre)Ifo>/Lyz2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ldlr<tm1Her>|Apoe<tm1Lmh>|Lyz2<+>|Lrp1<tm2Her>|Lyz2<tm1(cre)Ifo>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S7/SvEvBrd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to atherosclerosis
  http://purl.obolibrary.org/obo/MP_0005339

文献

http://purl.org/net/cito/citesAsAuthority

• L. Hu, et.al., Macrophage low-density lipoprotein receptor-related protein deficiency enhances atherosclerosis in ApoE/LDLR double knockout mice., Arteriosclerosis, thrombosis, and vascular biology, 2006, 26
  http://rdf.ncbi.nlm.nih.gov/pubmed/17038633