increased susceptibility to atherosclerosis_Esr1<tm1.1Mma>/Esr1<tm1.1Mma>,Ldlr<tm1Her>/Ldlr<tm1Her>

http://metadb.riken.jp/0005339I129S2SvPas129S7SvEvBrdEsr1tm11MmaEsr1tm11MmaLdlrtm1HerLdlrtm1HerEsr1tm11MmaLdlrtm1Her

increased susceptibility to atherosclerosis_Esr1<tm1.1Mma>/Esr1<tm1.1Mma>,Ldlr<tm1Her>/Ldlr<tm1Her>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• low density lipoprotein receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:96765
• estrogen receptor 1 (alpha)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1352467

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Esr1<tm1.1Mma>/Esr1<tm1.1Mma>,Ldlr<tm1Her>/Ldlr<tm1Her>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Esr1<tm1.1Mma>|Ldlr<tm1Her>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129S7/SvEvBrd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to atherosclerosis
  http://purl.obolibrary.org/obo/MP_0005339

文献

http://purl.org/net/cito/citesAsAuthority

• Audrey. Billon-Galés, et.al., The transactivating function 1 of estrogen receptor alpha is dispensable for the vasculoprotective actions of 17beta-estradiol., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/19188600