decreased susceptibility to atherosclerosis_Apoe<tm1Unc>/Apoe<tm1Unc>,Ccr2<tm1Ifc>/Ccr2<tm1Ifc>,Cx3cl1<tm1Lira>/Cx3cl1<tm1Lira>

http://metadb.riken.jp/0005341B6CgApoetm1UncCx3cl1tm1LiraCcr2tm1IfcApoetm1UncApoetm1UncCcr2tm1IfcCcr2tm1IfcCx3cl1tm1LiraCx3cl1tm1LiraApoetm1UncCx3cl1tm1LiraCcr2tm1Ifc

decreased susceptibility to atherosclerosis_Apoe<tm1Unc>/Apoe<tm1Unc>,Ccr2<tm1Ifc>/Ccr2<tm1Ifc>,Cx3cl1<tm1Lira>/Cx3cl1<tm1Lira>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• chemokine (C-C motif) receptor 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:106185
• apolipoprotein E
  http://metadb.riken.jp/db/mgi_rdf/MGI:88057
• chemokine (C-X3-C motif) ligand 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1097153

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apoe<tm1Unc>/Apoe<tm1Unc>,Ccr2<tm1Ifc>/Ccr2<tm1Ifc>,Cx3cl1<tm1Lira>/Cx3cl1<tm1Lira>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Apoe<tm1Unc>|Cx3cl1<tm1Lira>|Ccr2<tm1Ifc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6.Cg-Apoe<tm1Unc> Cx3cl1<tm1Lira> Ccr2<tm1Ifc>

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased susceptibility to atherosclerosis
  http://purl.obolibrary.org/obo/MP_0005341

文献

http://purl.org/net/cito/citesAsAuthority

• Noah. Saederup, et.al., Fractalkine deficiency markedly reduces macrophage accumulation and atherosclerotic lesion formation in CCR2-/- mice: evidence for independent chemokine functions in atherogenesis., Circulation, 2008, 117
  http://rdf.ncbi.nlm.nih.gov/pubmed/18165355