abnormal circulating corticosterone level_Crh<tm1Maj>/Crh<tm1Maj>

http://metadb.riken.jp/0005345I129S2SvPasC57BL6Crhtm1MajCrhtm1MajCrhtm1Maj

abnormal circulating corticosterone level_Crh<tm1Maj>/Crh<tm1Maj>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• corticotropin releasing hormone
  http://metadb.riken.jp/db/mgi_rdf/MGI:88496

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Crh<tm1Maj>/Crh<tm1Maj>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Crh<tm1Maj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal circulating corticosterone level
  http://purl.obolibrary.org/obo/MP_0005345

文献

http://purl.org/net/cito/citesAsAuthority

• K H. Jeong, et.al., Normal suppression of the reproductive axis following stress in corticotropin-releasing hormone-deficient mice., Endocrinology, 1999, 140
  http://rdf.ncbi.nlm.nih.gov/pubmed/10098506
• M. Venihaki, et.al., Corticotropin-releasing hormone regulates IL-6 expression during inflammation., The Journal of clinical investigation, 2001, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/11602623
• L. Jacobson, et.al., CRH deficiency impairs but does not block pituitary-adrenal responses to diverse stressors., Neuroendocrinology, 2000, 71
  http://rdf.ncbi.nlm.nih.gov/pubmed/10686522
• Pauline M. Anton, et.al., Corticotropin-releasing hormone (CRH) requirement in Clostridium difficile toxin A-mediated intestinal inflammation., Proceedings of the National Academy of Sciences of the United States of America, 2004, 101
  http://rdf.ncbi.nlm.nih.gov/pubmed/15159534
• Kyeong-Hoon. Jeong, et.al., Impaired leptin expression and abnormal response to fasting in corticotropin-releasing hormone-deficient mice., Endocrinology, 2004, 145
  http://rdf.ncbi.nlm.nih.gov/pubmed/15033910