increased susceptibility to autoimmune disorder_Cd28<tm1Shr>/Cd28<tm1Shr>,Ctla4<tm1Shr>/Ctla4<+>

http://metadb.riken.jp/0005350C129S4Cd28tm1ShrCtla4tm1ShrCd28tm1ShrCd28tm1ShrCtla4tm1ShrCtla4Ctla4tm1ShrCd28tm1ShrCtla4

increased susceptibility to autoimmune disorder_Cd28<tm1Shr>/Cd28<tm1Shr>,Ctla4<tm1Shr>/Ctla4<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cytotoxic T-lymphocyte-associated protein 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:88556
• CD28 antigen
  http://metadb.riken.jp/db/mgi_rdf/MGI:88327

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cd28<tm1Shr>/Cd28<tm1Shr>,Ctla4<tm1Shr>/Ctla4<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ctla4<tm1Shr>|Cd28<tm1Shr>|Ctla4<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• C.129S4-Cd28<tm1Shr> Ctla4<tm1Shr>

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to autoimmune disorder
  http://purl.obolibrary.org/obo/MP_0005350

文献

http://purl.org/net/cito/citesAsAuthority

• Jung-Hyun. Park, et.al., 'Coreceptor tuning': cytokine signals transcriptionally tailor CD8 coreceptor expression to the self-specificity of the TCR., Nature immunology, 2007, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/17873878