decreased susceptibility to prion infection_Cxcr5<tm1.1Namt>/Cxcr5<tm1.1Namt>,Tg(Itgax-cre)1-1Reiz/0,Tg(Prnp)a20Cwe/0

http://metadb.riken.jp/0005363IC57BL6C57BL6JCBACxcr5tm11NamtCxcr5tm11NamtTgItgaxcre11Reiz0TgPrnpa20Cwe0TgPrnpa20CweTgItgaxcre11ReizCxcr5tm11Namt

decreased susceptibility to prion infection_Cxcr5<tm1.1Namt>/Cxcr5<tm1.1Namt>,Tg(Itgax-cre)1-1Reiz/0,Tg(Prnp)a20Cwe/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1-1, Boris Reizis
  http://metadb.riken.jp/db/mgi_rdf/MGI:3763247
• chemokine (C-X-C motif) receptor 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:103567
• transgene insertion a20, Charles Weissmann
  http://metadb.riken.jp/db/mgi_rdf/MGI:2652457

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cxcr5<tm1.1Namt>/Cxcr5<tm1.1Namt>,Tg(Itgax-cre)1-1Reiz/0,Tg(Prnp)a20Cwe/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Prnp)a20Cwe|Tg(Itgax-cre)1-1Reiz|Cxcr5<tm1.1Namt>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * C57BL/6J * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased susceptibility to prion infection
  http://purl.obolibrary.org/obo/MP_0005363

文献

http://purl.org/net/cito/citesAsAuthority

• Barry M. Bradford, et.al., Oral Prion Disease Pathogenesis Is Impeded in the Specific Absence of CXCR5-Expressing Dendritic Cells., Journal of virology, 2017, 91
  http://rdf.ncbi.nlm.nih.gov/pubmed/28275192