increased susceptibility to prion infection_Prnp<tm1Cwe>/Prnp<tm1Cwe>,Tg(PRNP)45Jcol/Tg(PRNP)45Jcol

http://metadb.riken.jp/0005364I129129S7SvEvBrdC57BL6FVBNPrnptm1CwePrnptm1CweTgPRNP45JcolTgPRNP45JcolTgPRNP45JcolPrnptm1Cwe

increased susceptibility to prion infection_Prnp<tm1Cwe>/Prnp<tm1Cwe>,Tg(PRNP)45Jcol/Tg(PRNP)45Jcol

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 45, John Collinge
  http://metadb.riken.jp/db/mgi_rdf/MGI:5760242
• prion protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:97769

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Prnp<tm1Cwe>/Prnp<tm1Cwe>,Tg(PRNP)45Jcol/Tg(PRNP)45Jcol

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(PRNP)45Jcol|Prnp<tm1Cwe>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * 129S7/SvEvBrd * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to prion infection
  http://purl.obolibrary.org/obo/MP_0005364

文献

http://purl.org/net/cito/citesAsAuthority

• Emmanuel A. Asante, et.al., BSE prions propagate as either variant CJD-like or sporadic CJD-like prion strains in transgenic mice expressing human prion protein., The EMBO journal, 2002, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/12456643