axon degeneration_Slc12a6<tm1Garo>/Slc12a6<tm1Garo>,Tg(Syn1-cre)671Jxm/0

http://metadb.riken.jp/0005405I129C57BL6CBASlc12a6tm1GaroSlc12a6tm1GaroTgSyn1cre671Jxm0TgSyn1cre671JxmSlc12a6tm1Garo

axon degeneration_Slc12a6<tm1Garo>/Slc12a6<tm1Garo>,Tg(Syn1-cre)671Jxm/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 671, Jamey Marth
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176054
• solute carrier family 12, member 6
  http://metadb.riken.jp/db/mgi_rdf/MGI:2135960

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Slc12a6<tm1Garo>/Slc12a6<tm1Garo>,Tg(Syn1-cre)671Jxm/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Syn1-cre)671Jxm|Slc12a6<tm1Garo>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• axon degeneration
  http://purl.obolibrary.org/obo/MP_0005405

文献

http://purl.org/net/cito/citesAsAuthority

• Masoud. Shekarabi, et.al., Loss of neuronal potassium/chloride cotransporter 3 (KCC3) is responsible for the degenerative phenotype in a conditional mouse model of hereditary motor and sensory neuropathy associated with agenesis of the corpus callosum., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, 32
  http://rdf.ncbi.nlm.nih.gov/pubmed/22423107