abnormal heart size_Gata4<tm1.1Sad>/Gata4<tm1.1Sad>,Tg(Myh6-Map2k1*)1Jmol/0,Tg(Myh7-cre)1Jmk/0

http://metadb.riken.jp/0005406I129S1Sv129X1SvJFVBGata4tm11SadGata4tm11SadTgMyh6Map2k11Jmol0TgMyh7cre1Jmk0Gata4tm11SadTgMyh6Map2k11JmolTgMyh7cre1Jmk

abnormal heart size_Gata4<tm1.1Sad>/Gata4<tm1.1Sad>,Tg(Myh6-Map2k1*)1Jmol/0,Tg(Myh7-cre)1Jmk/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• GATA binding protein 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:95664
• transgene insertion 1, Jeffery D Molkentin
  http://metadb.riken.jp/db/mgi_rdf/MGI:3054165
• transgene insertion 1, Jeffery D Molkentin
  http://metadb.riken.jp/db/mgi_rdf/MGI:3766500

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gata4<tm1.1Sad>/Gata4<tm1.1Sad>,Tg(Myh6-Map2k1*)1Jmol/0,Tg(Myh7-cre)1Jmk/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gata4<tm1.1Sad>|Tg(Myh6-Map2k1*)1Jmol|Tg(Myh7-cre)1Jmk

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal heart size
  http://purl.obolibrary.org/obo/MP_0005406

文献

http://purl.org/net/cito/citesAsAuthority

• Jop H. van Berlo, et.al., Serine 105 phosphorylation of transcription factor GATA4 is necessary for stress-induced cardiac hypertrophy in vivo., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/21746915