abnormal circulating protein level_Apoe<tm1Lmh>/Apoe<tm1Lmh>,Ldlr<tm1Her>/Ldlr<tm1Her>,Lrp1<tm2Her>/Lrp1<tm2Her>,Tg(Mx1-cre)29-4Her/0

http://metadb.riken.jp/0005416I129S7SvEvBrdC57BL6JSJLApoetm1LmhApoetm1LmhLdlrtm1HerLdlrtm1HerLrp1tm2HerLrp1tm2HerTgMx1cre294Her0Lrp1tm2HerApoetm1LmhLdlrtm1HerTgMx1cre294Her

abnormal circulating protein level_Apoe<tm1Lmh>/Apoe<tm1Lmh>,Ldlr<tm1Her>/Ldlr<tm1Her>,Lrp1<tm2Her>/Lrp1<tm2Her>,Tg(Mx1-cre)29-4Her/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 29-4, Joachim Herz
  http://metadb.riken.jp/db/mgi_rdf/MGI:2180898
• apolipoprotein E
  http://metadb.riken.jp/db/mgi_rdf/MGI:88057
• low density lipoprotein receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:96765
• low density lipoprotein receptor-related protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:96828

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apoe<tm1Lmh>/Apoe<tm1Lmh>,Ldlr<tm1Her>/Ldlr<tm1Her>,Lrp1<tm2Her>/Lrp1<tm2Her>,Tg(Mx1-cre)29-4Her/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lrp1<tm2Her>|Apoe<tm1Lmh>|Ldlr<tm1Her>|Tg(Mx1-cre)29-4Her

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6J * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal circulating protein level
  http://purl.obolibrary.org/obo/MP_0005416

文献

http://purl.org/net/cito/citesAsAuthority

• Sonia M S. Espirito Santo, et.al., Hepatic low-density lipoprotein receptor-related protein deficiency in mice increases atherosclerosis independent of plasma cholesterol., Blood, 2004, 103
  http://rdf.ncbi.nlm.nih.gov/pubmed/14739216
• Niels. Bovenschen, et.al., LDL receptor cooperates with LDL receptor-related protein in regulating plasma levels of coagulation factor VIII in vivo., Blood, 2005, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/15840700