abnormal pro-B cell morphology_Rad50<tm2Jpt>/Rad50<tm2Jpt>,Smc1a<tm1Mbk>/Smc1a<tm1Mbk>

http://metadb.riken.jp/0005432I129S1Sv129S7SvEvBrdC57BL6Rad50tm2JptRad50tm2JptSmc1atm1MbkSmc1atm1MbkRad50tm2JptSmc1atm1Mbk

abnormal pro-B cell morphology_Rad50<tm2Jpt>/Rad50<tm2Jpt>,Smc1a<tm1Mbk>/Smc1a<tm1Mbk>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• RAD50 double strand break repair protein
  http://metadb.riken.jp/db/mgi_rdf/MGI:109292
• structural maintenance of chromosomes 1A
  http://metadb.riken.jp/db/mgi_rdf/MGI:1344345

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rad50<tm2Jpt>/Rad50<tm2Jpt>,Smc1a<tm1Mbk>/Smc1a<tm1Mbk>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rad50<tm2Jpt>|Smc1a<tm1Mbk>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S7/SvEvBrd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal pro-B cell morphology
  http://purl.obolibrary.org/obo/MP_0005432

文献

http://purl.org/net/cito/citesAsAuthority

• Monica. Morales, et.al., The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor., Genes & development, 2005, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/16357220