abnormal platelet physiology_Arhgef3<tm1(KOMP)Wtsi>/Arhgef3<tm1(KOMP)Wtsi>

http://metadb.riken.jp/0005464IC57BL6NArhgef3tm1KOMPWtsiArhgef3tm1KOMPWtsiArhgef3tm1KOMPWtsi

abnormal platelet physiology_Arhgef3<tm1(KOMP)Wtsi>/Arhgef3<tm1(KOMP)Wtsi>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Rho guanine nucleotide exchange factor (GEF) 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1918954

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Arhgef3<tm1(KOMP)Wtsi>/Arhgef3<tm1(KOMP)Wtsi>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Arhgef3<tm1(KOMP)Wtsi>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal platelet physiology
  http://purl.obolibrary.org/obo/MP_0005464

文献

http://purl.org/net/cito/citesAsAuthority

• Siying. Zou, et.al., SNP in human ARHGEF3 promoter is associated with DNase hypersensitivity, transcript level and platelet function, and Arhgef3 KO mice have increased mean platelet volume., PloS one, 2017, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/28542600