increased thyroxine level_Pten<tm1Hwu>/Pten<+>,Tg(Nkx2-1-cre)2Sand/0

http://metadb.riken.jp/0005470I129S4SvJaeBALBcC57BL6Ptentm1HwuPtenTgNkx21cre2Sand0PtenPtentm1HwuTgNkx21cre2Sand

increased thyroxine level_Pten<tm1Hwu>/Pten<+>,Tg(Nkx2-1-cre)2Sand/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583
• transgene insertion 2, Stewart Anderson
  http://metadb.riken.jp/db/mgi_rdf/MGI:3773079

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pten<tm1Hwu>/Pten<+>,Tg(Nkx2-1-cre)2Sand/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pten<+>|Pten<tm1Hwu>|Tg(Nkx2-1-cre)2Sand

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * BALB/c * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased thyroxine level
  http://purl.obolibrary.org/obo/MP_0005470

文献

http://purl.org/net/cito/citesAsAuthority

• Caterina. Tiozzo, et.al., Embryonic epithelial Pten deletion through Nkx2.1-cre leads to thyroid tumorigenesis in a strain-dependent manner., Endocrine-related cancer, 2012, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/22167068