pancreatic islet hyperplasia_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Alb-cre)21Mgn/0

http://metadb.riken.jp/0005491I129S4SvJaeC57BL6JDBA2FVBInsrtm1KhnInsrtm1KhnTgAlbcre21Mgn0TgAlbcre21MgnInsrtm1Khn

pancreatic islet hyperplasia_Insr<tm1Khn>/Insr<tm1Khn>,Tg(Alb-cre)21Mgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 21, Mark A Magnuson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176226
• insulin receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:96575

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Insr<tm1Khn>/Insr<tm1Khn>,Tg(Alb-cre)21Mgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Alb-cre)21Mgn|Insr<tm1Khn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6J * DBA/2 * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• pancreatic islet hyperplasia
  http://purl.obolibrary.org/obo/MP_0005491

文献

http://purl.org/net/cito/citesAsAuthority

• Rohit N. Kulkarni, et.al., PDX-1 haploinsufficiency limits the compensatory islet hyperplasia that occurs in response to insulin resistance., The Journal of clinical investigation, 2004, 114
  http://rdf.ncbi.nlm.nih.gov/pubmed/15372107