retinal pigment epithelium atrophy_Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Tg(Slc16a8-cre/ERT2,-EGFP)1Moss/0

http://metadb.riken.jp/0005548I129SSvEvC57BL6CBAGtROSA26Sortm1DTAJpmbGtROSA26SorTgSlc16a8creERT2EGFP1Moss0GtROSA26SorGtROSA26Sortm1DTAJpmbTgSlc16a8creERT2EGFP1Moss

retinal pigment epithelium atrophy_Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Tg(Slc16a8-cre/ERT2,-EGFP)1Moss/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Steven E Moss
  http://metadb.riken.jp/db/mgi_rdf/MGI:4399746
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(DTA)Jpmb>/Gt(ROSA)26Sor<+>,Tg(Slc16a8-cre/ERT2,-EGFP)1Moss/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gt(ROSA)26Sor<+>|Gt(ROSA)26Sor<tm1(DTA)Jpmb>|Tg(Slc16a8-cre/ERT2,-EGFP)1Moss

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• retinal pigment epithelium atrophy
  http://purl.obolibrary.org/obo/MP_0005548

文献

http://purl.org/net/cito/citesAsAuthority

• Rebecca. Longbottom, et.al., Genetic ablation of retinal pigment epithelial cells reveals the adaptive response of the epithelium and impact on photoreceptors., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/19850870