increased circulating glucose level_Tg(INS-Il10)#Sar/0,Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>

http://metadb.riken.jp/0005559I129S2SvPasC57BL6JNODTgINSIl10Sar0Tnfrsf1atm1MakTnfrsf1atm1MakTgINSIl10SarTnfrsf1atm1Mak

increased circulating glucose level_Tg(INS-Il10)#Sar/0,Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• tumor necrosis factor receptor superfamily, member 1a
  http://metadb.riken.jp/db/mgi_rdf/MGI:1314884
• transgene insertion #, Nora Sarvetnick
  http://metadb.riken.jp/db/mgi_rdf/MGI:3622648

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(INS-Il10)#Sar/0,Tnfrsf1a<tm1Mak>/Tnfrsf1a<tm1Mak>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(INS-Il10)#Sar|Tnfrsf1a<tm1Mak>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6J * NOD

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating glucose level
  http://purl.obolibrary.org/obo/MP_0005559

文献

http://purl.org/net/cito/citesAsAuthority

• B. Balasa, et.al., Islet-specific expression of IL-10 promotes diabetes in nonobese diabetic mice independent of Fas, perforin, TNF receptor-1, and TNF receptor-2 molecules., Journal of immunology (Baltimore, Md. : 1950), 2000, 165
  http://rdf.ncbi.nlm.nih.gov/pubmed/10946317