increased circulating glucose level_Tg(INS-Il10)#Sar/0,Tnfrsf1b<tm1Mwm>/Tnfrsf1b<tm1Mwm>

http://metadb.riken.jp/0005559I129S2SvPasC57BL6JNODTgINSIl10Sar0Tnfrsf1btm1MwmTnfrsf1btm1MwmTnfrsf1btm1MwmTgINSIl10Sar

increased circulating glucose level_Tg(INS-Il10)#Sar/0,Tnfrsf1b<tm1Mwm>/Tnfrsf1b<tm1Mwm>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion #, Nora Sarvetnick
  http://metadb.riken.jp/db/mgi_rdf/MGI:3622648
• tumor necrosis factor receptor superfamily, member 1b
  http://metadb.riken.jp/db/mgi_rdf/MGI:1314883

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(INS-Il10)#Sar/0,Tnfrsf1b<tm1Mwm>/Tnfrsf1b<tm1Mwm>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tnfrsf1b<tm1Mwm>|Tg(INS-Il10)#Sar

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6J * NOD

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating glucose level
  http://purl.obolibrary.org/obo/MP_0005559

文献

http://purl.org/net/cito/citesAsAuthority

• B. Balasa, et.al., Islet-specific expression of IL-10 promotes diabetes in nonobese diabetic mice independent of Fas, perforin, TNF receptor-1, and TNF receptor-2 molecules., Journal of immunology (Baltimore, Md. : 1950), 2000, 165
  http://rdf.ncbi.nlm.nih.gov/pubmed/10946317