increased circulating glucose level_Sirt6<tm1.1Cxd>/Sirt6<tm1.1Cxd>,Tg(Alb1-cre)1Dlr/0

http://metadb.riken.jp/0005559I129S6SvEvTacFVBNSirt6tm11CxdSirt6tm11CxdTgAlb1cre1Dlr0Sirt6tm11CxdTgAlb1cre1Dlr

increased circulating glucose level_Sirt6<tm1.1Cxd>/Sirt6<tm1.1Cxd>,Tg(Alb1-cre)1Dlr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• sirtuin 6
  http://metadb.riken.jp/db/mgi_rdf/MGI:1354161
• transgene insertion 1, Derek LeRoith
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176944

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Sirt6<tm1.1Cxd>/Sirt6<tm1.1Cxd>,Tg(Alb1-cre)1Dlr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Sirt6<tm1.1Cxd>|Tg(Alb1-cre)1Dlr

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating glucose level
  http://purl.obolibrary.org/obo/MP_0005559

文献

http://purl.org/net/cito/citesAsAuthority

• Hyun-Seok. Kim, et.al., Hepatic-specific disruption of SIRT6 in mice results in fatty liver formation due to enhanced glycolysis and triglyceride synthesis., Cell metabolism, 2010, 12
  http://rdf.ncbi.nlm.nih.gov/pubmed/20816089